Before Class Assignment

• read section 22.6 

• chirality
• amino acids
• amide functional group
• the protein biopolymer
  

Learning Objectives

• recognize a chiral carbon centre
• recognise polar and non-polar amino acids
  
• understand the primary chemical structure of a protein, made from amino acid units

Extra Material:

• download the static picture file (these are pictures of some of the structures we'll look at in class; it is a .pdf file)
• download the RASMOL VIEWER (this is an executable file for viewing 3D structures on a Windows machine)
• many other free viewers are available on the internet, by searching "protein visualization software xxx" where xxx = your computer/operating system type
• there are also apps for mobile devices, e.g., xxx in the Apple Apps store (I don't have an Android or Blackberry device, so I'm not sure about apps on them)
  
• some notes on how to use the Rasmol program (and a link to the full manual)
  

• human proinsulin, ubiquitin, bacterial β-amylase
  

• Chapter 22: 7, 83, 89, 101, 103, 129, 147, 159
  

Before Class Assignment

• none (22.6)

• levels of structure in proteins (primary, secondary, and tertiary structure)
• nucleic acids
• DNA structure

Learning Objectives

• understand how protein structures' shapes form in three dimensions
• understand and identify the three building blocks that make up a nucleic acid (phosphate, ribose, base)
• understand the three-dimensional structure of the deoxyribonucleic acid polymer (DNA)
• understand the mechanism of DNA self-replication and learn how to amplify DNA through the polymerase chain reaction (PCR)
  

• DNA double strand
  

• Chapter 22: 105
  

Before Class Assignment

• none (22.6)

• RNA
  
• protein bioynthesis
• lipids

Learning Objectives

• learn the structure of ribonucleic acid (RNA)
• learn the Central Dogma, i.e. how the information encoded on DNA is used to create molecules
• understand the structure of the class of non-polar biomolecules (lipids)
  

• RNA-protein complex, cholesterol, oleic acid, elaidic acid, a triglyceride fat, phospholipid, phospholipid monolayer, phospholipid bilayer

• Chapter 22: 107, 109, 158
  

Before Class Assignment

• read section 21.7
  

• carbohydrates
• bioinorganic molecules

Learning Objectives

• understand the structures of simple sugars, and the two ways they can connect to form polymeric structures (carbohydrates)
• understand the structure of the porphyrin ring and its coordination chemistry in various biologically important molecules
  

• glucose, cellulose, starch, Vitamin B12, chlorophyll, hemoglobin, myoglobin, lobster hemocyanin
  

• Chapter 22: 97, 99

COURSE EVALUATION DAY!